Last edited by Zolot
Friday, August 7, 2020 | History

7 edition of Protocols for Oligonucleotides and Analogs found in the catalog.

Protocols for Oligonucleotides and Analogs

Synthesis and Properties (Methods in Molecular Biology)

by Sudhir Agrawal

  • 346 Want to read
  • 22 Currently reading

Published by Humana Press .
Written in English

    Subjects:
  • Cellular biology,
  • Organic chemistry,
  • Synthesis,
  • Nucleotides,
  • Science,
  • Science/Mathematics,
  • Chemistry - Organic,
  • Derivatives,
  • Oligonucleotides

  • The Physical Object
    FormatPaperback
    Number of Pages502
    ID Numbers
    Open LibraryOL8253549M
    ISBN 100896032477
    ISBN 109780896032477

    Leading researchers summarize and describe their experience and techniques for synthesizing oligonucleotides and their analogs. The protocols presented cover all DNA analogs that have been studied to date and constitute the single most extensive source of knowledge about DNA chemistry available. (source: Nielsen Book Data). Oligonucleotide analogues We can synthesise a wide range of backbone and sugar-modified oligos such as phosphorothioates, 2′-O-methyl RNA and many others. Please enquire about specific modifications.

    Oligonucleotide analogues with cationic backbone linkages. Beilstein Journal of Organic Chemistry , 14, DOI: /bjoc Jolanta Brzezinska, Wojciech Markiewicz. Non-Nucleosidic Analogues of Polyaminonucleosides and Their Influence on Thermodynamic Properties of Derived Oligonucleotides. This book examines the research and development fields of oligonucleotide (ON) therapeutics, covering topics from the study of antisense and anti-gene effects to drug discovery and development, exploring wide-ranging methods and protocols for therapeutic applications involving ONs.

    A stepwise protocol using acid treatment for the final deprotection allowed the preparation of polypyrimidine oligonucleotides carrying longer and arginine-rich peptides. An ELISA-based test using the oligonucleotide-citrullinated peptide conjugates was developed for the detection of anti-citrullinated protein/peptide antibodies in human serum. oligonucleotides, the conventional methodology has proved to be somewhat inefficient and costly. Therefore, efforts are afoot to develop economical and rapid protocols to produce these molecules in _____ *Author for correspondence: E-mail: [email protected], Tel.: +91 .


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Protocols for Oligonucleotides and Analogs by Sudhir Agrawal Download PDF EPUB FB2

When first conceived, not only was the aim of Protocols for Oligo­ nucleotides and Protocols for Oligonucleotides and Analogs book to provide wide coverage of the ohgonuc- otide chemistry field for readers who are well versed within the field, but also to give investigators just entering into the field a new perspective.

When first conceived, not only was the aim of Protocols for Oligo­ nucleotides and Analogs to provide wide coverage of the ohgonuc- otide chemistry field for readers who are well versed within the field, but also to give investigators just entering into the field a new perspective.

The very first. Protocols for Oligonucleotides and Analogs: Synthesis and Properties by Sudhir Agrawal (Editor) | Editorial Reviews. Paperback () $ Ship This Item — Qualifies for Free Shipping Publish your book with B&N.

Learn More. The B&N Mastercard® Pages: Description: When first conceived, not only was the aim of Protocols for Oligo nucleotides and Analogs to provide wide coverage of the ohgonuc- otide chemistry field for readers who are well versed within the field, but also to give investigators just entering into the field a new perspective.

The very first book on this topic was edited and. Protocols for oligonucleotides and analogs by Sudhir Agrawal,Humana Press edition, in EnglishPages: Book Review Protocols for Oligonucleotides and Analogs. Synthesis and Properties (Methods in Molecular Biology/20) Edited by Sudhir Agrawal Published The Humana Press Inc., Totowa, NJ pages ISBN 0 7 $ (paperback) Whereas much of.

Presented here are reliable protocols for disulfide conjugation that have been verified for both cationic and hydrophobic peptides as well as oligonucleotides containing deoxyribonucleosides, ribonucleosides, 2′‐O‐methylribonucleosides, locked nucleic acid (LNA) units, as well as phosphorothioate backbones.

Also presented are reliable. Protocols for Oligonucleotides and Analogs. Synthesis and Properties; (Methods in Molecular Biology/20) Edited by Sudhir Agrawal.

DAVID M. TIDD. THE UNIVERSITY OF LIVERPOOL, UK. Search for more papers by this author. DAVID M. TIDD. Agrawal, Protocols for Oligonucleotides and Analogs,Buch, Bücher schnell und portofrei Beachten Sie bitte die aktuellen Informationen unseres Partners DHL zu Liefereinschränkungen im Ausland.

Cite this protocol as: Uhlmann E., Peyman A. () Oligonucleotide Analogs Containing Dephospho-Internucleoside Linkages. In: Agrawal S. (eds) Protocols for Oligonucleotides and Analogs. Get this from a library. Protocols for oligonucleotides and analogs: synthesis and properties.

[Sudhir Agrawal;] -- The most extensive modern treatment of DNA chemistry available today. Protocols for Oligonucleotides and Analogs - along with its companion volume, Protocols for Oligonucleotide Conjugates - covers. Get this from a library. Protocols for oligonucleotides and analogs: synthesis and properties.

[Sudhir Agrawal;] -- Leading researchers summarize and describe their experience and techniques for synthesizing oligonucleotides and their analogs. The protocols presented cover all DNA analogs that have been studied to. When first conceived, not only was the aim of Protocols for Oligo­ nucleotides and Analogs to provide wide coverage of the ohgonuc- otide chemistry field for readers who are well versed within the field, but also to give investigators just entering into the field a new perspective.

The very first book on this topic was edited and published by. This book will be of interest to academic and industrial researchers, enabling both chemists and non-chemists to synthesize oligonucleotides and analogues for a wide variety of experimental purposes. Protocols For Oligonucleotides And Analogs.

Interest in oligonucleotide synthesis has expanded dramatically since the publication of M. Gait's book in this series in The process has been automated, new reagents have been developed, and the range of uses for the compounds produced has increased and continues to grow.

This volume provides practical guidance on oligonucleotide synthesis and methods for introducing modifications into. Oligonucleotide synthesis is the chemical synthesis of relatively short fragments of nucleic acids with defined chemical structure ().The technique is extremely useful in current laboratory practice because it provides a rapid and inexpensive access to custom-made oligonucleotides of the desired sequence.

Whereas enzymes synthesize DNA and RNA only in a 5' to 3' direction, chemical. Abstract. Protocols for Oligonucleotides and Analogs. Synthesis and Properties (Methods in Molecular Biology/20) Edited by Sudhir Agrawal Published The Humana Press Inc., Totowa, NJ pages ISBN 0 7 $ (paperback) Whereas much of the current wisdom in the biological application of antisense oligonucleotides and oligonucleotide analogues rests upon the extremely.

Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides describes the procedures and protocols related to the modification of nucleosides, nucleotides and oligonucleotides via Pd-mediated cross-coupling processes. The book highlights the growing area of nucleic acid modification and how Pd-mediated coupling reactions.

The scope of this Special Issue is to bring together reviews, original research articles and short communications covering all current aspects of the design, synthesis and characterization of both small molecules (nucleoside analogues) and oligomers from innovative synthesis to potential therapeutic applications, e.g.

the discovery and. A series of 5-(heteroaryl)-dU analogs were synthesized in good yield via palladium-catalyzed coupling of protected 5-iodo-2′-deoxyuridine with trialkyl-heteroarylstannanes and subsequently incorporated into antisense oligonucleotides exhibiting significant enhancement in thermal stability (Tm) for complimentary RNA.

20 Among several analogs. Click Download or Read Online button to Synthesis Of Therapeutic Oligonucleotides book pdf for free now. Synthesis Of Therapeutic Oligonucleotides. Protocols For Oligonucleotides And Analogs.

Author: Sudhir Agrawal ISBN: enabling both chemists and non-chemists to synthesize oligonucleotides and analogues for a wide.Oligonucleotides and Analogues: A Practical Approach,Fritz Eckstein, IRL Press, book in this series in The process has been automated, new reagents have been developed, Ribozyme Protocols, Philip C.

Turner,Science, pages. Ribozyme Protocols brings.Nucleoside phosphoramidites are derivatives of natural or synthetic are used to synthesize oligonucleotides, relatively short fragments of nucleic acid and their side phosphoramidites were first introduced in by Beaucage and Caruthers.

To avoid undesired side reactions, reactive hydroxy and exocyclic amino groups present in natural or synthetic nucleosides.